Description

Penicillin CAS NO 525-94-0 is a fundamental β-lactam antibiotic that serves as the parent compound for a vital class of antimicrobial agents. Its core value lies in its potent bactericidal activity against a wide spectrum of Gram-positive bacteria, making it a cornerstone in the development of life-saving pharmaceutical formulations. This high-purity active pharmaceutical ingredient (API) is essential for manufacturers in the pharmaceutical industry, particularly for producing injectable antibiotics and conducting critical research in microbiology and drug discovery.

Application

• Pharmaceutical API Manufacturing: Primary raw material for the synthesis of various penicillin-based antibiotic drugs and sterile injectable formulations.
• Microbiological Research: Used as a standard reference compound in laboratory studies of bacterial resistance, antibiotic efficacy, and mechanism of action.
• Cell Culture & Biotechnology: Employed in selective media preparation to prevent bacterial contamination in eukaryotic cell cultures and bioprocessing.
• Veterinary Medicine: Key ingredient in the production of antibiotics for treating bacterial infections in livestock and companion animals.
• Standards & Calibration: Serves as a certified reference material (CRM) for quality control and analytical method validation in regulatory and quality assurance laboratories.

Basic Information

Product Name	Penicillin
CAS No.	525-94-0
Molecular Formula	C16H18N2O4S
Molecular Weight	334.39 g/mol
Synonyms	Benzylpenicillin; Penicillin G; 6-Phenylacetamidopenicillanic Acid; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid; Crystapen; Pentid; Pfizerpen; Free Penicillin Acid
EINECS	208-357-6

Quality Control

Our Penicillin is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch is tested against relevant pharmacopoeial specifications (such as USP/EP) for identity, purity, and potency. A comprehensive Certificate of Analysis (COA), detailing results for assay, related substances, residual solvents, and microbiological quality, is provided to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 96.0% (on dried basis)
Water (Karl Fischer)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Optical Rotation	+280° to +310° (c=1 in water)
pH (1% solution)	2.5 - 4.0
Residual Solvents (GC)	Complies with ICH guidelines
Bacterial Endotoxins	< 0.25 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.