Description

(20S)-3β,16β-Dihydroxy-5α-Pregnane-20-Carboxylic Acid γ-Lactone is a high-purity steroidal lactone compound, serving as a critical intermediate in advanced pharmaceutical synthesis. Its value lies in providing a structurally defined, high-quality building block essential for the research and production of complex steroid-based active pharmaceutical ingredients (APIs). This product is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in steroid chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development and manufacture of steroidal drugs, including certain classes of diuretics, anti-hypertensives, and anti-inflammatory agents.
• Research & Development: Used as a reference standard and starting material in organic chemistry research, particularly in studies involving steroid structure-activity relationships (SAR).
• Fine Chemical Synthesis: Serves as a chiral building block for the synthesis of more complex, biologically active steroid derivatives and analogs.
• Biochemical Studies: Employed in metabolic pathway research and enzymatic studies related to steroid biosynthesis and transformation.

Basic Information

Item	Details
Product Name	(20S)-3β,16β-Dihydroxy-5α-Pregnane-20-Carboxylic Acid γ-Lactone
CAS No.	514-33-0
Molecular Formula	C21H30O4
Molecular Weight	346.46 g/mol
Synonyms	3β,16β-Dihydroxy-5α-pregnan-20-carboxylic acid γ-lactone; 16β-Hydroxy-3β-hydroxy-5α-pregnan-20-carboxylic acid γ-lactone; (20S)-3β,16β-Dihydroxy-5α-pregnan-20-carboxylic acid γ-lactone; 5α-Pregnane-20-carboxylic acid, 3β,16β-dihydroxy-, γ-lactone, (20S)-; 3β,16β-Dihydroxy-5α-pregnan-20-oic acid γ-lactone; 16β-Hydroxy-3β-hydroxypregnan-20-carbolactone; A steroidal γ-lactone intermediate.
EINECS	208-178-3

Quality Control

Our (20S)-3β,16β-Dihydroxy-5α-Pregnane-20-Carboxylic Acid γ-Lactone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.