Description

Procaine Penicillin G is a crystalline salt formed from penicillin G and procaine, widely recognized for its sustained-release antibacterial properties. This compound is essential for formulating long-acting injectable antibiotic preparations, providing a critical tool for managing bacterial infections in veterinary and specific medical contexts. It is primarily utilized by pharmaceutical manufacturers, veterinary medicine producers, and research institutions developing antimicrobial therapies.

Application

• Veterinary Injectable Antibiotics: A key active pharmaceutical ingredient (API) in long-acting formulations for treating bacterial infections in livestock, poultry, and companion animals.
• Human Pharmaceutical Intermediates: Used in the synthesis and formulation of specific penicillin-based antibiotic preparations requiring a prolonged release profile.
• Bacteriological Research: Serves as a standard or reference compound in microbiological studies and antimicrobial susceptibility testing.
• API Manufacturing: A critical raw material for pharmaceutical companies producing finished dosage forms of procaine benzylpenicillin.
• Aquaculture: Employed in medicated feeds or treatments for controlling bacterial diseases in farmed fish and shellfish.

Basic Information

Product Name	Procaine Penicillin G
CAS No.	54-35-3
Molecular Formula	C29H38N4O6S
Molecular Weight	570.70 g/mol
Synonyms	Procaine Benzylpenicillin; Penicillin G Procaine; Benzylpenicillin Procaine Salt; Procaine Penicillin; Procaine Salt of Penicillin G; Wycillin; Crysticillin; Duracillin; 4-Amino-N-(2-diethylaminoethyl)benzamide compound with (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
EINECS	200-203-3

Quality Control

Our Procaine Penicillin G is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards, including identity, potency, and impurity profile verification. Certificates of Analysis (COA) are provided with every shipment, detailing results for key parameters such as assay, water content, and specific impurities. We can supply material compliant with various pharmacopoeial standards (e.g., USP, BP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	96.0% - 102.0% (on anhydrous basis)
Water (Karl Fischer)	≤ 4.0%
pH (suspension)	5.0 - 7.5
Specific Optical Rotation	+165° to +180°

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.