Description

Ethyl 3,4,5-Trifluorobenzoate is a high-purity fluorinated aromatic ester, a key building block in advanced organic synthesis. Its trifluoromethyl-substituted benzoate structure makes it a versatile intermediate for creating complex molecules with enhanced properties. This compound is essential for R&D and production in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients with improved metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter surface properties, enhance chemical resistance, and improve durability.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, esterifications, and as a protecting group in multi-step synthetic pathways.

Basic Information

Product Name	Ethyl 3,4,5-Trifluorobenzoate
CAS No.	495405-09-9
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	3,4,5-Trifluorobenzoic Acid Ethyl Ester; Ethyl 3,4,5-Trifluorobenzoate; Benzoic acid, 3,4,5-trifluoro-, ethyl ester; Ethyl 3,4,5-Trifluorobenzenecarboxylate; 495405-09-9; Ethyl 3,4,5-Trifluorophenylcarboxylate; 3,4,5-Trifluorobenzoic Acid, Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 3,4,5-Trifluorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.