Description

4-Hydroxybenzyl Methanethiosulfonate is a specialized organosulfur compound with a reactive methanethiosulfonate (MTS) group. This chemical is valued for its role as a versatile bioconjugation and protein modification reagent, enabling site-specific labeling and crosslinking in biochemical research. It is primarily used by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for developing advanced therapeutics and diagnostic tools.

Application

• Bioconjugation Reagent: For site-specific labeling of proteins, antibodies, and peptides with fluorophores, biotin, or other functional molecules.
• Protein Engineering & Modification: Used to introduce thiol-reactive groups or create disulfide bonds to study protein structure and function.
• Crosslinking Agent: In the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems.
• Biochemical Probe Synthesis: A key building block for creating activity-based probes to study enzyme mechanisms.
• Surface Functionalization: For modifying biosensor surfaces, nanoparticles, and chromatography media to enhance specificity.
• Pharmaceutical Intermediate: In the research and development of novel small-molecule therapeutics.

Basic Information

Product Name	4-Hydroxybenzyl Methanethiosulfonate
CAS No.	491868-12-3
Molecular Formula	C8H8O3S2
Molecular Weight	216.28 g/mol
Synonyms	p-Hydroxybenzyl methanethiosulfonate; (4-Hydroxybenzyl) methanesulfonothioate; MTS-4-Hydroxybenzyl; 4-Hydroxybenzyl MTS; Benzyl alcohol, 4-hydroxy-, methanethiosulfonate; 4-(Methanethiosulfonylmethyl)phenol; 4-Hydroxybenzyl methanesulfonothioate
EINECS	Contact for details

Quality Control

Our 4-Hydroxybenzyl Methanethiosulfonate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.