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4-(4-Fluoro-2-Methylphenyl)Benzoic Acid CAS NO 479079-38-4
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CAS No.:479079-38-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4-(4-Fluoro-2-Methylphenyl)Benzoic Acid is a high-purity fluorinated aromatic carboxylic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular structure, which incorporates both a benzoic acid moiety and a substituted fluorophenyl ring, making it an essential building block for creating complex molecules with tailored properties. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and functional materials.
Application
- Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
- Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
- Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated aromatic cores essential in high-performance electronic display materials and organic light-emitting diodes (OLEDs).
- Polymer Modification: Acts as a monomer or cross-linking agent to introduce fluorine-containing aromatic groups into polymer chains, improving chemical resistance and thermal stability.
- Organic Synthesis Building Block: Employed in Suzuki-Miyaura, Buchwald-Hartwig, and other cross-coupling reactions to construct complex biaryl systems prevalent in medicinal chemistry.
- Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries for high-throughput screening.
Basic Information
| Product Name | 4-(4-Fluoro-2-Methylphenyl)Benzoic Acid |
| CAS No. | 479079-38-4 |
| Molecular Formula | C14H11FO2 |
| Molecular Weight | 230.24 g/mol |
| Synonyms | [4-(4-Fluoro-2-methylphenyl)phenyl]formic acid; 4'-Fluoro-2'-methyl[1,1'-biphenyl]-4-carboxylic acid; 4-(4-Fluoro-2-methylphenyl)benzoic acid; 2-Methyl-4-fluorobiphenyl-4'-carboxylic acid; Biphenyl-4-carboxylic acid, 4'-fluoro-2'-methyl-; 4-Carboxy-4'-fluoro-2'-methylbiphenyl; 4-Fluoro-2-methylbiphenyl-4'-carboxylic acid |
| EINECS | Contact for details |
Quality Control
Our production of 4-(4-Fluoro-2-Methylphenyl)Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured and tested in facilities operating under cGMP principles where applicable. Comprehensive analytical testing, including HPLC, NMR, and GC-MS, is performed to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize moisture absorption.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
| Single Unknown Impurity (HPLC) | ≤ 0.5% |
| Total Impurities (HPLC) | ≤ 2.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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