Description

Methyl 2-(4-Fluorophenyl)-2-Methylpropanoate is a high-purity fluorinated ester building block of significant interest in advanced organic synthesis. Its value lies in its unique structure, which incorporates both a fluorinated aromatic ring and a sterically hindered ester group, making it a versatile intermediate for creating complex molecules. This compound is primarily needed by research and development chemists and process scale-up teams within the pharmaceutical and agrochemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated components in electronic display and lighting materials.
• Advanced Polymer Modification: Employed to introduce fluorinated phenyl groups into polymer chains, altering surface properties and chemical resistance.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and method development in academic and industrial R&D laboratories.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of tailored intermediates for client-specific projects.

Basic Information

Product Name	Methyl 2-(4-Fluorophenyl)-2-Methylpropanoate
CAS No.	476429-17-1
Molecular Formula	C11H13FO2
Molecular Weight	196.22 g/mol
Synonyms	2-(4-Fluorophenyl)-2-methylpropanoic acid methyl ester; Methyl 2-(p-fluorophenyl)-2-methylpropionate; 4-Fluoro-α,α-dimethylbenzeneacetic acid methyl ester; Methyl 4-fluoro-α,α-dimethylbenzeneacetate; p-Fluoro-α,α-dimethylphenylacetic acid methyl ester; Methyl p-fluoro-α,α-dimethylphenylacetate; 476429-17-1; Methyl 2-methyl-2-(4-fluorophenyl)propanoate
EINECS	Contact for details

Quality Control

Our Methyl 2-(4-Fluorophenyl)-2-Methylpropanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical data are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed in a dry and inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.