Description

4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine-1-(β-D-ribofuranosyl-5’-triphosphate) is a sophisticated nucleotide analog derivative, representing a key building block in advanced biochemical research and development. This compound is critical for its role in modulating specific enzymatic pathways and studying nucleoside-based mechanisms. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutic agents, particularly in the fields of oncology and virology. The CAS number for this compound is 476371-80-9.

Application

• Biochemical Research: Serves as a vital precursor or intermediate in the study of kinase inhibition and nucleotide metabolism.
• Pharmaceutical Development: Used in the synthesis and screening of potential drug candidates targeting specific disease pathways.
• Enzymology Studies: Acts as a substrate or inhibitor for enzymes like kinases and phosphotransferases to elucidate their function and mechanism.
• Probe and Diagnostic Agent Synthesis: A key component in creating labeled probes for molecular biology assays and diagnostic applications.
• Antiviral & Anticancer Research: Investigated for its potential activity in disrupting viral replication or uncontrolled cell proliferation.
• Nucleic Acid Chemistry: Employed in the development of modified nucleotides for advanced oligonucleotide synthesis.

Basic Information

Product Name	4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine-1-(β-D-ribofuranosyl-5’-triphosphate)
CAS No.	476371-80-9
Molecular Formula	C22H25N6O14P3
Molecular Weight	690.39 g/mol
Synonyms	4-Amino-3-benzyl-1-(5-O-{[hydroxy({[hydroxy(phosphonooxy)phosphoryl]oxy})phosphoryl]-β-D-ribofuranosyl})-1H-pyrazolo[3,4-d]pyrimidine; 3-Benzyl-4-aminopyrazolopyrimidine riboside triphosphate; 4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1-riboside 5'-triphosphate; Bz-4-APP riboside triphosphate; Bz-APP-TP; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this high-purity biochemical adheres to stringent quality protocols. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (UV/VIS)	≥ 90%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.