Description

3,6-Difluoro-2-Methylbenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and methyl substituents, which are essential for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and manufacturing of advanced herbicides and pesticides, where the difluoro-methylbenzoic acid core contributes to enhanced biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, enhancing material properties such as chemical resistance, thermal stability, and surface characteristics.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and constructing complex molecular architectures in academic and industrial laboratories.

Basic Information

Product Name	3,6-Difluoro-2-Methylbenzoic Acid
CAS No.	459836-92-1
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	2-Methyl-3,6-difluorobenzoic Acid; 3,6-Difluoro-o-toluic Acid; 2-Methyl-3,6-difluorobenzoic Acid; Benzoic acid, 3,6-difluoro-2-methyl-; 459836-92-1; 3,6-Difluoro-2-methyl-benzoic acid
EINECS	Contact for details

Quality Control

Our 3,6-Difluoro-2-Methylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.