Description

2-Fluoro-3-Iodobenzoic Acid is a high-purity, multi-functional halogenated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, provides exceptional versatility for creating complex molecular architectures through cross-coupling and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators, leveraging the bioactivity of halogenated aromatic systems.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis, such as Suzuki-Miyaura and Buchwald-Hartwig cross-coupling reactions.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and polymers where halogen atoms fine-tune electronic properties and molecular packing.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags for imaging and diagnostic applications due to the reactivity of the iodine moiety.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global R&D pipelines.

Basic Information

Product Name	2-Fluoro-3-Iodobenzoic Acid
CAS No.	447464-03-1
Molecular Formula	C7H4FIO2
Molecular Weight	265.01 g/mol
Synonyms	3-Iodo-2-fluorobenzoic Acid; Benzoic acid, 2-fluoro-3-iodo-; 2-Fluoro-3-iodobenzenecarboxylic acid; 447464-03-1; 2-F-3-I-BA
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Iodobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and ICP-MS for heavy metal screening, to ensure it meets the exacting standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals (ICP-MS)	< 10 ppm
Loss on Drying	< 0.5%
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.