Description

2-Fluoro-5-Methoxy-3-Methylbenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique substitution pattern makes it valuable for constructing complex molecules with tailored properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery and development programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Chemical Research & Development: A versatile reagent for introducing fluorine and methoxy-substituted benzoic acid motifs into more complex molecular architectures in academic and industrial labs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Item	Details
Product Name	2-Fluoro-5-Methoxy-3-Methylbenzoic Acid
CAS No.	447463-91-4
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	3-Methyl-2-fluoro-5-methoxybenzoic Acid; 2-Fluoro-5-methoxy-3-methyl-benzoic Acid; 5-Methoxy-3-methyl-2-fluorobenzoic Acid; Benzoic acid, 2-fluoro-5-methoxy-3-methyl-; 447463-91-4; 2-Fluoro-5-methoxy-m-toluic acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production of 2-Fluoro-5-Methoxy-3-Methylbenzoic Acid adheres to current Good Manufacturing Practice (GMP) principles where applicable. Every batch is analytically verified using advanced techniques like HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.