Description

n-(4-Ethynylphenyl)-4-Fluorobenzenecarboxamide is a specialized organic compound featuring a terminal alkyne and a fluorinated aromatic amide structure. This unique molecular architecture makes it a valuable high-purity building block for advanced chemical synthesis. It is primarily utilized by research and development teams in the pharmaceutical and advanced materials sectors for applications requiring precise molecular modification, such as in the development of active pharmaceutical ingredients (APIs) and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry for creating targeted molecular libraries.
• Click Chemistry Reagent: The terminal alkyne group enables its use in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, a cornerstone of bioconjugation and polymer science.
• Ligand and Catalyst Development: Used in the synthesis of specialized ligands or organometallic complexes for catalytic applications.
• Advanced Material Research: Acts as a monomer or functionalizing agent in the development of specialty polymers, dendrimers, or surface-modified materials.
• Agrochemical Synthesis: Potential intermediate in the development of new crop protection agents with enhanced properties.
• Life Sciences Tool: Employed in probe and sensor development for biochemical assays and imaging techniques.

Basic Information

Product Name	n-(4-Ethynylphenyl)-4-Fluorobenzenecarboxamide
CAS No.	439095-42-8
Molecular Formula	C15H10FNO
Molecular Weight	239.25 g/mol
Synonyms	4-Fluoro-N-(4-ethynylphenyl)benzamide; N-(4-Ethynylphenyl)-4-fluorobenzamide; 4'-Ethynyl-4-fluorobenzanilide; p-Ethynylphenyl 4-fluorobenzoate amide; 4-Fluorobenzoic acid (4-ethynylphenyl)amide; CAS 439095-42-8
EINECS	Contact for details

Quality Control

Our production of n-(4-Ethynylphenyl)-4-Fluorobenzenecarboxamide adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.