Description

2H-3-Benzazepin-2-One, 1-Amino-1,3,4,5-Tetrahydro-3-Methyl-, Hydrochloride (1:1), (1S)- is a high-purity, single-enantiomer benzazepine derivative, serving as a critical chiral building block and intermediate in advanced pharmaceutical synthesis. Its value lies in providing a stereochemically defined scaffold essential for developing novel therapeutic agents with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and process development of central nervous system (CNS) drugs and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel drug candidates, particularly in neuroscience.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Medicinal Chemistry Research: Core structure for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry: Intermediate in the scale-up and optimization of synthetic routes for complex active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Potential use in pharmacological assays to study receptor interactions and enzyme inhibition.

Basic Information

Item	Detail
Product Name	2H-3-Benzazepin-2-One, 1-Amino-1,3,4,5-Tetrahydro-3-Methyl-, Hydrochloride (1:1), (1S)-
CAS No.	425663-71-4
Molecular Formula	C11H15ClN2O
Molecular Weight	226.70 g/mol
Synonyms	(1S)-1-Amino-3-methyl-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one hydrochloride; (S)-1-Amino-3-methyl-4,5-dihydro-1H-3-benzazepin-2(3H)-one hydrochloride; 1-Amino-3-methyl-4,5-dihydro-1H-3-benzazepin-2(3H)-one hydrochloride (S-enantiomer); (S)-1-Amino-3-methyl-1,2,3,5-tetrahydro-4H-3-benzazepin-4-one hydrochloride; (1S)-1-Amino-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one hydrochloride; UNII-7V3V7G31QN; 7V3V7G31QN; (S)-1-Amino-3-methyl-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one HCl
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques (HPLC, NMR, MS) to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.