Description

4-Fluoro-2-Methylsulfanyl-Benzoic Acid is a fluorinated benzoic acid derivative bearing a methylthio substituent, serving as a versatile and high-value synthetic building block. This compound is critical for introducing specific fluorine and sulfur-containing motifs into target molecules, enabling fine-tuning of their physicochemical and biological properties. It is primarily sought after by research chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances metabolic stability and bioavailability.
• Liquid Crystal & OLED Material Research: Serves as a starting material for creating fluorinated aromatic cores in advanced electronic and display materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and carboxylation reactions to construct complex molecular architectures.
• Chemical Biology Probe Development: Utilized to create tagged or modified molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	4-Fluoro-2-Methylsulfanyl-Benzoic Acid
CAS No.	410545-51-6
Molecular Formula	C8H7FO2S
Molecular Weight	186.20 g/mol
Synonyms	2-(Methylthio)-4-fluorobenzoic Acid; 4-Fluoro-2-(methylsulfanyl)benzoic Acid; 4-Fluoro-2-(methylthio)benzoic Acid; Benzoic acid, 4-fluoro-2-(methylthio)-; 4-Fluoro-2-methylmercaptobenzoic Acid; 2-Methylsulfanyl-4-fluorobenzoic Acid; 4-Fluoro-2-methylsulfanylbenzoic acid; 4-Fluoro-2-(methylsulfanyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methylsulfanyl-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from techniques including HPLC, NMR, and MS. Our standard grade meets a typical purity specification of ≥97% (HPLC), with custom purification available to meet specific project requirements, including pharmaceutical development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.