Description

(4'-Trifluoromethylbiphenyl-4-Yl)Acetic Acid CAS NO 406188-98-5 is a high-purity, functionalized biphenyl derivative featuring a trifluoromethyl group and an acetic acid moiety. This compound is a critical advanced pharmaceutical intermediate valued for its role in modulating the physicochemical properties of target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting inflammation, oncology, and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for the development of specialized organic electronic materials and liquid crystal compounds due to its rigid biphenyl core and polar functional groups.
• Chemical Research: Employed in academic and industrial laboratories as a versatile scaffold for medicinal chemistry and material science exploration.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	(4'-Trifluoromethylbiphenyl-4-Yl)Acetic Acid
CAS No.	406188-98-5
Molecular Formula	C15H11F3O2
Molecular Weight	280.24 g/mol
Synonyms	2-[4'-(Trifluoromethyl)[1,1'-biphenyl]-4-yl]acetic Acid; 4'-(Trifluoromethyl)biphenyl-4-acetic Acid; [4'-(Trifluoromethyl)[1,1'-biphenyl]-4-yl]acetic Acid; (4'-Trifluoromethyl-[1,1'-biphenyl]-4-yl)-acetic Acid; Biphenyl-4-acetic acid, 4'-(trifluoromethyl)-; p-(p-Trifluoromethylphenyl)phenylacetic Acid
EINECS	Contact for details

Quality Control

Our (4'-Trifluoromethylbiphenyl-4-Yl)Acetic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The product is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.