Description

4-Hydroxy-2'-Trifluoromethyl-Biphenyl-3-Carboxylic Acid is a high-purity, multi-functional biphenyl derivative that serves as a critical advanced intermediate in modern organic synthesis. Its unique structure, featuring both a carboxylic acid and a trifluoromethyl group, makes it an exceptionally valuable building block for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a core component in the synthesis of high-performance liquid crystals for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport or host materials in OLED device fabrication.
• Polymer Modification: Employed to introduce functional biphenyl units into polymer backbones, enhancing thermal and mechanical properties.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Item	Details
Product Name	4-Hydroxy-2'-Trifluoromethyl-Biphenyl-3-Carboxylic Acid
CAS No.	400744-89-0
Molecular Formula	C14H9F3O3
Molecular Weight	282.22 g/mol
Synonyms	3'-Hydroxy-4'-(trifluoromethyl)biphenyl-4-carboxylic acid; 2'-Trifluoromethyl-4-hydroxybiphenyl-3-carboxylic acid; 4-Hydroxy-2'-(trifluoromethyl)-1,1'-biphenyl-3-carboxylic acid; 3-Carboxy-4-hydroxy-2'-trifluoromethylbiphenyl; Biphenyl-3-carboxylic acid, 4-hydroxy-2'-(trifluoromethyl)-; [1,1'-Biphenyl]-3-carboxylic acid, 4-hydroxy-2'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 4-Hydroxy-2'-Trifluoromethyl-Biphenyl-3-Carboxylic Acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency meet the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.