Description

2'-Deoxyuridine 5'-Monophosphate Disodium Salt is a nucleotide monophosphate analog, a critical building block in biochemical research and pharmaceutical development. This high-purity compound is essential for studying DNA synthesis, repair mechanisms, and as a precursor for the synthesis of more complex nucleoside derivatives. It is primarily utilized by researchers and manufacturers in the biotechnology, pharmaceutical, and diagnostic industries.

Application

• Biochemical Research: Used as a substrate or intermediate in enzymatic studies, particularly those involving thymidylate synthase and other nucleotide metabolism pathways.
• Pharmaceutical Synthesis: Serves as a key starting material or intermediate in the synthesis of antiviral and anticancer nucleoside analogs.
• Molecular Biology: Employed in the study of DNA replication and repair processes, and as a component in certain in vitro transcription/translation systems.
• Diagnostic Reagent Manufacturing: Used in the production of reagents for molecular diagnostics and genetic testing kits.
• Enzyme Inhibition Studies: Acts as a potential inhibitor for enzymes involved in nucleotide synthesis, useful for drug discovery programs.

Basic Information

Product Name	2'-Deoxyuridine 5'-Monophosphate Disodium Salt
CAS No.	42155-08-8
Molecular Formula	C9H11N2Na2O8P
Molecular Weight	368.13 g/mol
Synonyms	dUMP Disodium Salt; 2'-Deoxyuridylic Acid Disodium Salt; Deoxyuridine Monophosphate Disodium Salt; 5'-dUMP Na2; dUMP Na2; Uridine, 2'-deoxy-, 5'-(dihydrogen phosphate), disodium salt; 2'-Deoxy-5'-uridylic acid disodium salt
EINECS	Contact for details

Quality Control

Our 2'-Deoxyuridine 5'-Monophosphate Disodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and tests for residual solvents and endotoxins where applicable. Certificates of Analysis (COA) with lot-specific data are provided to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
pH (5% Solution)	6.5 - 8.5
Endotoxin (where specified)	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.