Description

3-[(2-Methyl-2-Propenyl)Oxyiminomethyl]Rifamycin Sv is a chemically modified derivative of the potent ansamycin antibiotic, rifamycin SV, designed to enhance its pharmacological profile. This semi-synthetic compound is critical for pharmaceutical research and development, particularly in the synthesis of novel antibacterial agents targeting resistant strains. It is primarily needed by pharmaceutical manufacturers, R&D laboratories, and academic institutions engaged in developing next-generation antibiotics and studying bacterial RNA polymerase inhibition.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of advanced rifamycin-based antibiotics.
• Antibacterial Research: Used in microbiological and biochemical research to study mechanisms of action against Gram-positive bacteria and Mycobacterium tuberculosis.
• Structure-Activity Relationship (SAR) Studies: Essential for medicinal chemistry programs aiming to optimize the potency, spectrum, and pharmacokinetics of ansamycin-class drugs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• API Development: Investigated in the development of new Active Pharmaceutical Ingredients (APIs) with improved stability or efficacy.

Basic Information

Product Name	3-[(2-Methyl-2-Propenyl)Oxyiminomethyl]Rifamycin Sv
CAS No.	41970-69-8
Molecular Formula	C₃₈H₄₇N₃O₁₃
Molecular Weight	753.80 g/mol
Synonyms	3-[(2-Methylprop-2-en-1-yl)oxyiminomethyl]rifamycin SV; 3-Isopropenyloximinomethylrifamycin SV; Rifamycin SV 3-(2-methyl-2-propenyl)oxime; Rifamycin SV derivative; Antibiotic derivative 41970-69-8; (E)-3-((2-Methylallyloxy)iminomethyl)rifamycin SV; 3-O-(2-Methyl-2-propenyl)oximinorifamycin SV
EINECS	Contact for details

Quality Control

Our 3-[(2-Methyl-2-Propenyl)Oxyiminomethyl]Rifamycin Sv is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and stringent control of related substances. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). For long-term storage, consider conditions of 2-8°C. Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Orange to reddish-brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.