Description

3-[(2-Isopropoxyethoxy)Iminomethyl]Rifamycin Sv CAS NO 41970-62-1 is a key semi-synthetic derivative of the potent ansamycin antibiotic rifamycin. This compound serves as a crucial intermediate in the synthesis of advanced rifamycin-based pharmaceuticals, offering a strategic modification point for enhancing drug efficacy and pharmacokinetic profiles. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel antibacterial and antitubercular agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of next-generation rifamycin antibiotics, such as rifampicin and rifabutin analogs.
• Antibacterial Research: Used in medicinal chemistry research to develop new compounds targeting drug-resistant bacterial strains, including Mycobacterium tuberculosis.
• Biochemical Studies: Employed in studies investigating the mechanism of action of RNA polymerase inhibition by ansamycin antibiotics.
• API Development: Serves as a precursor in the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs) with improved stability or bioavailability.

Basic Information

Product Name	3-[(2-Isopropoxyethoxy)Iminomethyl]Rifamycin Sv
CAS No.	41970-62-1
Molecular Formula	C₄₀H₅₅N₃O₁₃
Molecular Weight	809.89 g/mol
Synonyms	3-[(2-Isopropoxyethoxy)Iminomethyl]Rifamycin S; Rifamycin SV, 3-[(2-isopropoxyethoxy)iminomethyl]-; 3-Formylrifamycin SV O-(2-isopropoxyethyl)oxime; Rifamycin SV derivative; 3-(N-Isopropoxyethyl)iminomethylrifamycin SV; Antibiotic X 510; (E)-3-(((2-Isopropoxyethoxy)imino)methyl)rifamycin SV
EINECS	Contact for details

Quality Control

Our 3-[(2-Isopropoxyethoxy)Iminomethyl]Rifamycin Sv is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Orange to Reddish-Brown Powder
Identification (IR)	Conforms to Reference Spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.