Description

3-[[[(3,7,11-Trimethyl-2,6,10-Dodecatrienyl)Oxy]Imino]Methyl]Rifamycin is a chemically modified derivative of the potent ansamycin antibiotic rifamycin, designed to enhance its pharmacological profile. This semi-synthetic compound is critical for research and development in advanced antimicrobial therapies, offering a foundation for novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) targeting resistant bacterial infections.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of next-generation rifamycin-class antibiotics with improved efficacy and reduced resistance.
• Antimicrobial Research: Used as a reference standard and experimental compound in microbiological studies to investigate mechanisms of action against Gram-positive bacteria and Mycobacterium tuberculosis.
• Medicinal Chemistry: A vital building block for structural-activity relationship (SAR) studies aimed at optimizing pharmacokinetic properties like solubility and metabolic stability.
• API Development: Employed in the development and scale-up processes for new antibacterial active pharmaceutical ingredients under GMP conditions.
• Biochemical Tool: Functions as a specific inhibitor in enzymatic assays to study bacterial RNA polymerase.

Basic Information

Product Name	3-[[[(3,7,11-Trimethyl-2,6,10-Dodecatrienyl)Oxy]Imino]Methyl]Rifamycin
CAS No.	41887-55-2
Molecular Formula	C46H63N3O12
Molecular Weight	850.01 g/mol
Synonyms	Rifamycin Derivative 41887-55-2; 3-[(3,7,11-Trimethyldodeca-2,6,10-trienyloxy)iminomethyl]rifamycin; Rifamycin O-alkyloxime derivative; (3-Formylrifamycin SV) O-(3,7,11-trimethyl-2,6,10-dodecatrienyl)oxime; Ansamycin antibiotic derivative; Antibiotic X 87-55-2; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3-[[[(3,7,11-Trimethyl-2,6,10-Dodecatrienyl)Oxy]Imino]Methyl]Rifamycin is produced and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Orange to Reddish-Brown Powder
Identification (IR)	Conforms to Reference Spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.