Description

3-[(1-Propylpentyl)Oxyiminomethyl]Rifamycin Sv is a chemically modified derivative of the potent ansamycin antibiotic, rifamycin SV. This semi-synthetic compound is engineered to enhance specific pharmacological properties, making it a critical intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing novel antibacterial agents and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of next-generation rifamycin-class antibiotics.
• Antibacterial Research: Used in microbiological and biochemical studies to investigate mechanisms of action against resistant bacterial strains.
• Structure-Activity Relationship (SAR) Studies: Essential for medicinal chemistry programs aiming to optimize the pharmacokinetic and pharmacodynamic profiles of ansamycin derivatives.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• API Development: Investigated as a precursor in the development of new Active Pharmaceutical Ingredients (APIs) targeting mycobacterial infections.

Basic Information

Product Name	3-[(1-Propylpentyl)Oxyiminomethyl]Rifamycin Sv
CAS No.	41776-72-1
Molecular Formula	C₄₀H₅₅N₃O₁₂
Molecular Weight	769.89 g/mol
Synonyms	3-[(1-Propylpentyl)Oxyiminomethyl]Rifamycin; Rifamycin SV, 3-[(1-propylpentyl)oxyiminomethyl]-; 3-(O-[(1-Propylpentyl)oximino]methyl)rifamycin SV; Rifamycin SV oxime, 3-[(1-propylpentyl)oxyiminomethyl]-; 3-[(1-Propylpentyl)Oxyiminomethyl]Rifamycin S V; 41776-72-1; Rifamycin derivative 41776-72-1
EINECS	Contact for details

Quality Control

Our 3-[(1-Propylpentyl)Oxyiminomethyl]Rifamycin Sv is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Orange to reddish-brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.