Description

n-Acetyl-L-Aspartic Acid Anhydride is a high-purity, reactive anhydride derivative of the amino acid aspartic acid. This compound serves as a critical chiral building block and protecting group intermediate in sophisticated organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for the development of peptides, prodrugs, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of peptide-based drugs, prodrugs, and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in the study of enzyme mechanisms, as a substrate analog, and in the preparation of modified amino acids for proteomics.
• Peptide Synthesis: Acts as an acetylating agent and protecting group for the aspartic acid side chain during solid-phase and solution-phase peptide synthesis.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, chiral catalysts, and advanced materials.
• Neuroscience Research: Potential use in studies related to N-acetylaspartate (NAA) metabolism and its role in the nervous system.

Basic Information

Product Name	n-Acetyl-L-Aspartic Acid Anhydride
CAS No.	41148-79-2
Molecular Formula	C6H7NO5
Molecular Weight	173.12 g/mol
Synonyms	N-Acetyl-L-aspartic anhydride; (S)-2-Acetamidosuccinic anhydride; L-Aspartic acid, N-acetyl-, anhydride; Ac-Asp-OH anhydride; N-Acetylaspartic acid anhydride; N-Acetyl-DL-aspartic anhydride (related); NAA Anhydride
EINECS	Contact for details

Quality Control

Our n-Acetyl-L-Aspartic Acid Anhydride is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and decomposition. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.