Description

S(+)-Apomorphine Hydrochloride Hydrate is the pharmacologically active enantiomer of apomorphine, a potent dopamine receptor agonist. This high-purity compound is critical for advanced pharmaceutical research and development, particularly in the study and treatment of neurological disorders. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in neuroscience, Parkinson's disease research, and the development of central nervous system (CNS) therapeutics.

Application

• Pharmaceutical Active Pharmaceutical Ingredient (API): A key intermediate in the synthesis of advanced neurological medications.
• Neuroscience Research: Used as a selective D1/D2 dopamine receptor agonist in preclinical studies to investigate dopaminergic pathways.
• Parkinson's Disease Models: Employed in animal models to induce rotational behavior and study therapeutic interventions for motor control disorders.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Drug Delivery System Development: Investigated in formulations for subcutaneous injection or other delivery routes due to its rapid onset of action.
• Biochemical Assays: Utilized in receptor binding assays and functional cellular tests to screen for new CNS-active compounds.

Basic Information

Product Name	S(+)-Apomorphine Hydrochloride Hydrate
CAS No.	41035-30-7
Molecular Formula	C17H17NO2 • HCl • xH2O
Molecular Weight	303.78 (Anhydrous base), 340.26 (Anhydrous HCl salt)
Synonyms	(R)-(-)-Apomorphine Hydrochloride; (R)-Apomorphine HCl; (6aR)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol Hydrochloride; S-(-)-Apomorphine Hydrochloride; Apomorphine (R)-(-) Hydrochloride; Apomorphine Hydrochloride (R)-(-) Form; L-Apomorphine Hydrochloride; R-(-)-Apomorphine HCl; (-)-Apomorphine Hydrochloride
EINECS	Contact for details

Quality Control

Our S(+)-Apomorphine Hydrochloride Hydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing identity, purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Chiral Purity (HPLC)	≥99.0% (S-enantiomer)
Water Content (KF)	≤8.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.