Description

2-Methoxy-5-(Trifluoromethyl)Benzoic Acid is a high-value trifluoromethylated aromatic building block essential for advanced organic synthesis. This compound is prized for its ability to impart unique physicochemical properties, such as enhanced metabolic stability and lipophilicity, to target molecules. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Electronic Materials: A valuable monomer or intermediate for creating electron-deficient units in organic semiconductors and OLED materials.
• Advanced Polymer Chemistry: Incorporated as a modifying agent to create specialty polymers with improved chemical resistance and thermal properties.
• Chemical Research & Development: A versatile reagent for medicinal chemistry and process chemistry R&D, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-Methoxy-5-(Trifluoromethyl)Benzoic Acid
CAS No.	4864-01-1
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	5-(Trifluoromethyl)-2-methoxybenzoic Acid; 2-Methoxy-α,α,α-trifluoro-p-toluic Acid; 2-Methoxy-5-trifluoromethylbenzoic Acid; Benzoic acid, 2-methoxy-5-(trifluoromethyl)-; m-Trifluoromethyl-o-anisic Acid; 5-Trifluoromethyl-2-methoxybenzoic Acid; 2-Methoxy-5-(trifluoromethyl)benzoic acid; 2-Methoxy-5-trifluoromethyl-benzoic acid
EINECS	225-477-6

Quality Control

Our 2-Methoxy-5-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its acidic nature, ensure storage containers are made of compatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	148 - 152 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.