Description

3-Amino-4-(Trifluoromethyl)Benzoic Acid is a high-value trifluoromethylated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. This compound is prized for its unique combination of an amino group and a strongly electron-withdrawing trifluoromethyl group on the aromatic ring, enabling precise modulation of molecular properties. It is primarily utilized by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Design: Serves as a versatile scaffold for creating novel ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Incorporated into the synthesis of advanced polymers, liquid crystals, and organic electronic materials to fine-tune thermal and electronic properties.
• Chemical Research: Employed in academic and industrial laboratories for method development, structure-activity relationship (SAR) studies, and the creation of compound libraries.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and pigments with enhanced light-fastness and color properties.

Basic Information

Product Name	3-Amino-4-(Trifluoromethyl)Benzoic Acid
CAS No.	4857-33-4
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	3-Amino-4-(trifluoromethyl)benzoic acid; 4-(Trifluoromethyl)anthranilic acid; Benzoic acid, 3-amino-4-(trifluoromethyl)-; 3-Amino-α,α,α-trifluoro-p-toluic acid; 2-Amino-5-carboxybenzotrifluoride; 3-Amino-4-trifluoromethylbenzoic acid; 4-Carboxy-2-trifluoromethylaniline
EINECS	Contact for details

Quality Control

Our 3-Amino-4-(Trifluoromethyl)Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your internal quality standards and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept sealed to prevent absorption of atmospheric moisture, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	205 - 210 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.