Description

2'-Deoxycytidylyl-(3'-5')-Thymidine is a defined dinucleotide, specifically a cytidine-thymidine dimer, which serves as a fundamental building block in nucleic acid research and synthesis. This compound is critical for studying DNA structure, enzymatic processes, and for the custom synthesis of oligonucleotides. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require high-purity, well-characterized biochemical intermediates.

Application

• Oligonucleotide Synthesis: As a protected dimer phosphoramidite or solid support for automated DNA synthesis.
• Biochemical Research: Substrate for studying DNA polymerases, ligases, nucleases, and other DNA-modifying enzymes.
• Probe and Primer Development: A key intermediate in the manufacture of labeled probes, primers, and other molecular biology tools.
• Antisense & Therapeutic Oligo Development: Used in the research and early-stage development of antisense oligonucleotides and other nucleic acid-based therapeutics.
• Reference Standard: Serves as an analytical standard for quality control in oligonucleotide production and for method validation.

Basic Information

Item	Detail
Product Name	2'-Deoxycytidylyl-(3'-5')-Thymidine
CAS No.	4829-64-5
Molecular Formula	C19H25N5O12P
Molecular Weight	546.41 g/mol
Synonyms	d(CpT); Cytidylyl-(3'→5')-thymidine; Deoxycytidylyl-(3'-5')-thymidine; 5'-Thymidylyl-(3'→5')-2'-deoxycytidine; TpT (common misnomer); DNA dimer CpT; Dinucleotide CpT; pd(C-T)
EINECS	Contact for details

Quality Control

Our 2'-Deoxycytidylyl-(3'-5')-Thymidine is produced under strict quality management systems. Each batch is characterized and tested to ensure high purity and consistency, suitable for demanding research and development applications. Certificates of Analysis (COA) with detailed HPLC purity data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.