Description

Carbenicillin is a semi-synthetic, broad-spectrum penicillin antibiotic derived from the penicillin nucleus, 6-aminopenicillanic acid. Its primary value lies in its activity against a wide range of Gram-negative bacteria, including many Pseudomonas aeruginosa strains, making it a critical tool in research and development. This compound is essential for microbiologists, pharmaceutical researchers, and manufacturers involved in antibiotic susceptibility testing, molecular biology, and the development of novel therapeutic agents.

Application

• Microbiological Research & Assay Development: Used as a selective agent in culture media for the isolation and study of resistant bacterial strains.
• Pharmaceutical R&D: Serves as a key reference standard and intermediate in the research of β-lactam antibiotics and resistance mechanisms.
• Molecular Biology: Employed as a selective marker in genetic engineering and plasmid selection in bacterial systems.
• Antibiotic Susceptibility Testing (AST): A critical component in clinical and research laboratories to determine bacterial resistance profiles.
• Biochemical Studies: Used to investigate the structure and function of bacterial cell walls and penicillin-binding proteins (PBPs).
• Manufacturing of Diagnostic Kits: Incorporated into kits and reagents used for bacterial identification and antibiotic resistance testing.

Basic Information

Product Name	Carbenicillin
CAS No.	4697-36-3
Molecular Formula	C17H18N2O6S
Molecular Weight	378.40 g/mol
Synonyms	Carbenicillin; (2S,5R,6R)-6-[(Carboxy-2-thienylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; BRL 2064; Carbecin; Geopen; Pyopen; Carbenicillin Acid; α-Carboxy-2-thienylmethylpenicillin
EINECS	225-161-7

Quality Control

Our Carbenicillin is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via validated methods such as HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent internal specifications. We support research requiring traceable and high-purity biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 3.0%
pH (1% solution)	2.5 - 4.0
Specific Optical Rotation	+172° to +182° (c=1 in H2O)
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.