Description

2,3-Difluorobenzoic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its role in introducing the difluorobenzene moiety, which can significantly alter the electronic properties, metabolic stability, and bioavailability of target molecules. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, anti-cancer agents, and central nervous system (CNS) drugs where the difluoro motif enhances metabolic stability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to improved lipophilicity and target binding.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of fluorinated compounds for electronic displays and organic light-emitting diodes (OLEDs), influencing charge transport and emission properties.
• Polymer Modification: Employed to synthesize fluorinated monomers or additives that impart special properties like chemical resistance, low surface energy, or thermal stability to polymers.
• Chemical Research & Development: A versatile reagent in medicinal chemistry and material science R&D for structure-activity relationship (SAR) studies and novel compound library synthesis.
• Coordination Chemistry Ligand: The carboxylic acid and fluorine atoms can act as binding sites or influence electron density in metal-organic frameworks (MOFs) and catalysts.

Basic Information

Product Name	2,3-Difluorobenzoic Acid
CAS No.	4519-39-5
Molecular Formula	C7H4F2O2
Molecular Weight	158.10 g/mol
Synonyms	2,3-Difluorobenzoic Acid; Benzoic acid, 2,3-difluoro-; 2,3-Difluorobenzenecarboxylic acid; 2,3-Difluoro-benzoic acid; 2,3-Difluorobenzoic acid (CAS 4519-39-5); 2,3-Difluorobenzoic acid, 98+%; 2,3-Difluorobenzoic acid, 99%
EINECS	Contact for details

Quality Control

Our 2,3-Difluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	155°C - 160°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.