Description

6α-[(1-Oxohexyl)Amino]Penicillanic Acid is a key semi-synthetic penicillin derivative, primarily utilized as a crucial intermediate in the synthesis of advanced β-lactam antibiotics. Its value lies in providing a versatile chemical scaffold for developing novel antimicrobial agents with targeted activity. This compound is essential for pharmaceutical R&D laboratories and manufacturers focused on producing next-generation antibiotics to address evolving bacterial resistance.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of novel penicillin and cephalosporin-based antibiotics.
• Antimicrobial Research: Serves as a core structure for modifying side chains to develop new β-lactam compounds with improved efficacy and spectrum of activity.
• Process Chemistry: Used in scale-up and optimization studies for the commercial production of specialized antibiotic APIs (Active Pharmaceutical Ingredients).
• Biochemical Studies: Employed in research to study structure-activity relationships (SAR) and the mechanism of action of β-lactam drugs.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	6α-[(1-Oxohexyl)Amino]Penicillanic Acid
CAS No.	4493-18-9
Molecular Formula	C14H23N3O4S
Molecular Weight	329.42 g/mol
Synonyms	6-[(1-Oxohexyl)amino]penicillanic acid; 6-APA Hexanoyl Derivative; 6-Aminopenicillanic Acid Hexanoyl Amide; N-Hexanoyl-6-aminopenicillanic Acid; 6-(Hexanoylamino)penicillanic Acid; 6-APA Caproyl Amide; (2S,5R,6R)-6-[(Hexanoylamino)methyl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6α-[(1-Oxohexyl)Amino]Penicillanic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards suitable for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.