Description

3-Methylcytidine 5'-Monophosphate is a modified nucleotide monophosphate, a key building block in nucleic acid research and development. This compound is essential for studying RNA structure, function, and the biochemical pathways involving epigenetic modifications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for applications ranging from oligonucleotide synthesis to enzyme substrate studies.

Application

• Oligonucleotide Synthesis: Used as a modified phosphoramidite or solid-phase synthesis building block for creating research-grade RNA strands with specific methylation patterns.
• Biochemical Research: Serves as a critical substrate or standard in enzymatic studies, particularly for methyltransferases and other RNA-modifying enzymes.
• Antiviral Drug Development: Investigated as a potential nucleotide analog for the design of novel therapeutic agents targeting viral replication.
• Diagnostic Probe Development: Incorporated into nucleic acid probes to enhance specificity and stability in diagnostic assays and hybridization techniques.
• Epigenetics and RNA Biology: A vital tool for exploring the role of RNA methylation in gene expression regulation and cellular processes.
• Enzyme Kinetics & Inhibition Studies: Employed to study enzyme mechanisms and to screen for inhibitors in high-throughput drug discovery platforms.

Basic Information

Product Name	3-Methylcytidine 5'-Monophosphate
CAS No.	4343-64-0
Molecular Formula	C11H16N3O8P
Molecular Weight	349.23 g/mol
Synonyms	3-Methylcytidine 5'-phosphate; 5'-CMP, 3-methyl-; 3-Methyl-5'-CMP; 3-Methylcytidylic acid; 1-[(2R,3R,4R,5R)-3,4-Dihydroxy-5-(phosphonooxy)oxolan-2-yl]-4-(methylamino)pyrimidin-2-one; m3CMP; 3-Methylcytidine monophosphate; N3-Methylcytidine 5'-monophosphate
EINECS	Contact for details

Quality Control

Our 3-Methylcytidine 5'-Monophosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity (Enzymatic)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.