Description

Deoxyadenylyl-(3'-5')-Deoxyguanosine is a defined dinucleotide, specifically a deoxyadenosine-deoxyguanosine dimer, which serves as a fundamental building block in nucleic acid research and synthesis. This high-purity biochemical is critical for studying DNA structure, enzymatic processes, and for the controlled assembly of oligonucleotides. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in molecular biology, genomics, and therapeutic development.

Application

• Oligonucleotide Synthesis: As a protected dimer phosphoramidite or solid-phase synthesis intermediate for constructing specific DNA sequences.
• Biochemical Research: A substrate for studying DNA polymerases, ligases, nucleases, and other DNA-modifying enzymes.
• Diagnostic Probe Development: Used in the design and manufacture of probes for PCR, sequencing, and hybridization assays.
• Structural Studies: Serves as a model compound for NMR and X-ray crystallography to investigate DNA conformation and base-pair interactions.
• Antisense & Aptamer Research: A key component in the development of novel therapeutic oligonucleotides and sensing molecules.
• Quality Control Standard: Acts as a reference standard in analytical laboratories to validate methods for oligonucleotide purity and identity.

Basic Information

Product Name	Deoxyadenylyl-(3'-5')-Deoxyguanosine
CAS No.	4336-87-2
Molecular Formula	C20H25N9O11P
Molecular Weight	574.44 g/mol
Synonyms	d(ApG); Deoxyadenylyl-(3'→5')-deoxyguanosine; d(ApdG); Adenine deoxyribosyl-, 5'-(3'-deoxyguanylate); 5'-d(A)-3'-d(G); dA-dG dinucleotide; Deoxyadenosine-deoxyguanosine dimer; pd(A-G)
EINECS	Contact for details

Quality Control

Every batch of Deoxyadenylyl-(3'-5')-Deoxyguanosine is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the exacting requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by MS and/or NMR), and moisture content is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, desiccate at low temperature. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.