Description

N(1)-Methyl-2-Lysergic Acid Diethylamide is a specialized ergoline alkaloid derivative of significant interest in advanced chemical research and development. This compound is valued for its precise molecular structure, which serves as a critical intermediate and reference standard in pharmaceutical discovery and analytical chemistry. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and analytical service providers engaged in neurochemical studies, method development, and quality control of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel ergoline-based compounds and central nervous system (CNS) active agents.
• Analytical Chemistry & Method Development: Used as a high-purity certified reference material (CRM) for calibrating analytical instruments, validating HPLC, GC-MS, or LC-MS methods, and ensuring accuracy in quantitative analysis.
• Biochemical & Neurochemical Studies: Employed in academic and industrial research to investigate receptor binding affinities, metabolic pathways, and structure-activity relationships (SAR) within the ergoline class.
• Quality Control & Assurance: Acts as a critical standard for the identification, purity assessment, and impurity profiling of related active pharmaceutical ingredients (APIs) and finished drug products in GMP environments.
• Chemical Synthesis: Functions as a sophisticated building block for the custom synthesis of specialized derivatives for targeted research applications.

Basic Information

Product Name	N(1)-Methyl-2-Lysergic Acid Diethylamide
CAS No.	4238-85-1
Molecular Formula	C₂₁H₂₇N₃O
Molecular Weight	337.46 g/mol
Synonyms	1-Methyl-2-lysergic acid diethylamide; 1-Methyl-2-LSD; 1-Methyl-lysergic acid diethylamide; N(1)-Methyl-LSD; N1-Methyl-2-lysergic acid diethylamide; N1-Methyl-LSD; 9,10-Didehydro-N,1-diethyl-6-methylergoline-8β-carboxamide; (8β)-9,10-Didehydro-N,1-diethyl-6-methylergoline-8-carboxamide
EINECS	Contact for details

Quality Control

Our N(1)-Methyl-2-Lysergic Acid Diethylamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assay by HPLC, and impurity profiling. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all test results against stringent internal specifications. We support research and development with materials suitable for use as analytical reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). This material is strictly light-sensitive and must be protected from all light exposure during storage and handling to maintain stability and purity. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.