Description

5-Azacytosine is a heterocyclic organic compound and a pyrimidine nucleobase analog, recognized for its significant role as a biochemical tool and pharmaceutical intermediate. Its structural similarity to cytosine makes it a valuable compound for research into nucleoside metabolism, enzyme inhibition, and epigenetic modulation. This high-purity material is essential for pharmaceutical R&D, academic research, and the synthesis of advanced active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of nucleoside-based drugs, including antiviral and anticancer agents.
• Biochemical Research: Used as a cytosine analog to study DNA/RNA methylation, enzyme mechanisms (e.g., cytidine deaminase), and epigenetic processes.
• Antiviral Agent Development: Serves as a precursor in the research and development of novel antiviral compounds targeting viral replication.
• Oncology Research: Investigated for its potential in creating chemotherapeutic agents due to its ability to interfere with nucleic acid synthesis.
• Academic & Industrial R&D: A fundamental reagent in organic synthesis and medicinal chemistry projects within university and corporate laboratories.

Basic Information

Product Name	5-Azacytosine
CAS No.	4040-10-2
Molecular Formula	C3H4N4O
Molecular Weight	112.09 g/mol
Synonyms	4-Amino-1H-1,2,3-triazin-2(3H)-one; 4-Amino-1,2-dihydro-1,2,3-triazin-2-one; 5-Aza-2-oxocytosine; 2(1H)-Pyrimidinone, 4-amino-1,5-dihydro-; Azacytosine; 4-Amino-1,2,3-triazin-2(1H)-one; NSC 1895
EINECS	223-734-6

Quality Control

Our 5-Azacytosine is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. The product is tested against comprehensive specifications, including identity, assay, and impurity profiles using validated analytical methods such as HPLC and NMR. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.