Description

Dops CAS NO 492-46-6 is a high-purity chemical intermediate, also known as 3,4-Dihydroxyphenylserine (DOPS), which is critical for advanced pharmaceutical synthesis and biochemical research. Its primary value lies in its role as a precursor in the production of catecholamines and other neurologically active compounds, ensuring precise and reliable outcomes in complex manufacturing processes. This product is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on neurochemistry and drug development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of L-DOPS (Droxidopa), a medication used for neurogenic orthostatic hypotension.
• Biochemical Research: Used as a standard or reagent in studies of catecholamine biosynthesis, metabolism, and related enzymatic pathways.
• Fine Chemical Synthesis: Serves as a chiral building block for the preparation of more complex, optically active molecules in asymmetric synthesis.
• Neuropharmacology: Employed in preclinical research to investigate adrenergic and dopaminergic systems.
• Reference Standard: Utilized in analytical laboratories for method development and quality control of related pharmaceutical products.

Basic Information

Product Name	Dops
CAS No.	492-46-6
Molecular Formula	C9H11NO5
Molecular Weight	213.19 g/mol
Synonyms	3,4-Dihydroxyphenylserine; DOPS; L-threo-DOPS; Droxidopa Impurity; (-)-three-3,4-Dihydroxyphenylserine; Erythro-3,4-dihydroxy-L-phenylserine; L-erythro-3,4-Dihydroxyphenylserine; (2S,3R)-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid
EINECS	207-758-8

Quality Control

Our Dops is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines, and specifications can be aligned with customer requirements for specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; therefore, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and prolong shelf life.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range upon request
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.