Description

9,10-Didehydro-n-Ethyl-6-Methylergoline-8β-Carboxamide is a high-purity ergoline derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of complex bioactive molecules targeting neurological pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing novel therapeutic agents. Our supply is characterized by stringent quality control, ensuring reliability for sensitive applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex ergot alkaloid derivatives and potential active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in neurological and receptor-binding studies due to its ergoline scaffold.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for method development and quality control in analytical laboratories.
• Preclinical Development: Employed in early-stage drug discovery for pharmacokinetic and pharmacodynamic profiling of new chemical entities.
• Academic Research: Utilized in university and institutional labs for studying the structure-activity relationships (SAR) of ergoline compounds.
• Fine Chemical Synthesis: Intermediate for the custom synthesis of specialized, high-value compounds for contract research organizations (CROs).

Basic Information

Product Name	9,10-Didehydro-n-Ethyl-6-Methylergoline-8β-Carboxamide
CAS No.	478-99-9
Molecular Formula	C20H25N3O
Molecular Weight	323.43 g/mol
Synonyms	Lisuride; Lysuride; N-Ethyl-N'-[(8β)-6-methylergolin-8-yl]urea; 9,10α-Didehydro-N-ethyl-6-methylergoline-8β-carboxamide; Lised; Dopergin; Cuvalit; Proclacam; Revanil; Eunal
EINECS	207-534-6

Quality Control

Our 9,10-Didehydro-n-Ethyl-6-Methylergoline-8β-Carboxamide is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to relevant GMP principles for the production of advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.