Description

4-Fluorocinnamic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials. It is particularly sought after by research institutions and industrial manufacturers in the life sciences and specialty chemical sectors for creating novel compounds with enhanced biological activity and physical properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators that incorporate fluorinated motifs for improved efficacy.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Employed in the synthesis of specialty polymers and coatings where the fluorophenyl group imparts specific chemical resistance or surface properties.
• Biochemical Research: Utilized as a probe or substrate in enzymatic studies and for the development of fluorescence-based sensors and markers.
• Cross-Coupling Reactions: Acts as a versatile reactant in palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings for complex molecule assembly.

Basic Information

Product Name	4-Fluorocinnamic Acid
CAS No.	459-32-5
Molecular Formula	C9H7FO2
Molecular Weight	166.15 g/mol
Synonyms	(E)-3-(4-Fluorophenyl)acrylic Acid; trans-4-Fluorocinnamic Acid; 4-Fluorobenzeneacrylic Acid; p-Fluorocinnamic Acid; (E)-3-(4-Fluorophenyl)-2-propenoic Acid; 4-Fluorocinnameic Acid; 4-Fluorocinnaminsäure; FCA
EINECS	207-306-3

Quality Control

Every batch of 4-Fluorocinnamic Acid is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our standard grade meets typical research and industrial specifications, with custom purity levels available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	210°C - 215°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.