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3-(3-Fluorophenyl)Propionic Acid CAS NO 458-45-7


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CAS No.:458-45-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(3-Fluorophenyl)Propionic Acid is a versatile fluorinated aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atom and the propionic acid side chain, enabling precise molecular modifications. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific fluorinated motifs into target molecules.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules containing a fluorinated phenyl moiety.
  • Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity, stability, and metabolic profile.
  • Liquid Crystal & OLED Material Research: Acts as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
  • Polymer Modification: Employed to introduce fluorinated aromatic groups into polymer chains, altering properties like thermal stability, chemical resistance, and surface characteristics.
  • Chemical Biology & Proteomics: Useful as a linker or tagging reagent in bioconjugation chemistry and the development of chemical probes.
  • General Organic Synthesis: A valuable reagent for Friedel-Crafts acylation, esterification, amidation, and reduction reactions to create more complex fluorinated structures.

Basic Information

Product Name 3-(3-Fluorophenyl)Propionic Acid
CAS No. 458-45-7
Molecular Formula C9H9FO2
Molecular Weight 168.16 g/mol
Synonyms 3-(3-Fluorophenyl)propanoic acid; 3-Fluorohydrocinnamic acid; m-Fluorohydrocinnamic acid; (3-Fluorophenyl)propionic Acid; β-(3-Fluorophenyl)propionic Acid; 3-Fluoro-benzenepropanoic acid; NSC 406925
EINECS Contact for details

Quality Control

Our 3-(3-Fluorophenyl)Propionic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for each lot, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizers, bases, and sources of ignition.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥98.0%
Melting Point Contact for details
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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