Description

4-Fluorobenzoic Acid is a versatile fluorinated aromatic carboxylic acid, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atom, enabling precise modifications to molecular structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic rings to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can increase lipophilicity and biological activity.
• Liquid Crystal & Polymer Chemistry: Acts as a monomer or modifying agent in the creation of specialty polymers and liquid crystal displays (LCDs) to alter thermal and optical properties.
• Organic Synthesis Building Block: Employed in coupling reactions (e.g., Suzuki, Heck) and as a starting material for preparing derivatives like acid chlorides, esters, and amides for further functionalization.
• Research & Development: A standard reagent in medicinal chemistry and material science R&D for structure-activity relationship (SAR) studies and novel compound library generation.

Basic Information

Product Name	4-Fluorobenzoic Acid
CAS No.	456-22-4
Molecular Formula	C7H5FO2
Molecular Weight	140.11 g/mol
Synonyms	p-Fluorobenzoic Acid; 4-Fluorobenzenecarboxylic Acid; Benzoic acid, 4-fluoro-; para-Fluorobenzoic Acid; 4-FBA; FBA; 4-Fluorodracylic Acid; NSC 9235
EINECS	207-267-3

Quality Control

Our 4-Fluorobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 99.0%
Melting Point	182 - 186 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.