Description

4-Fluoro-3-Methylbenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 4-fluoro-3-methylbenzoyl moiety into target molecules, enabling the creation of complex chemical architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable, high-purity reagent for constructing active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated benzoyl group.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic components in electronic display and lighting materials.
• Polymer Chemistry: Employed as a monomer or modifying agent to introduce fluorine and aromaticity into polymer backbones, altering thermal and chemical resistance.
• Dyestuff and Pigment Production: Intermediate for synthesizing specialized fluorinated dyes and pigments with unique color fastness and properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new fluorinated compounds and reaction pathways.

Basic Information

Product Name	4-Fluoro-3-Methylbenzoyl Chloride
CAS No.	455-84-5
Molecular Formula	C8H6ClFO
Molecular Weight	172.58 g/mol
Synonyms	3-Methyl-4-fluorobenzoyl chloride; 4-Fluoro-m-toluoyl chloride; 4-Fluoro-3-methylbenzoic acid chloride; 3-Methyl-4-fluorobenzoic acid chloride; 4-Fluoro-3-methyl-benzoylchlorid; 4-Fluoro-3-methylbenzoylchloride; p-Fluoro-m-methylbenzoyl chloride
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Methylbenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong bases, alcohols, and amines. Due to its nature as a strong acid/organic solvent, it is recommended to handle and store under inert atmosphere (e.g., nitrogen) for extended periods to maintain optimal quality. Recommended storage temperature: 2-8°C for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.