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Methyl 3-Fluorobenzoate CAS NO 455-68-5


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CAS No.:455-68-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl 3-Fluorobenzoate is a versatile fluorinated aromatic ester, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic introduction of both a fluorine atom and a methyl ester group onto a benzene ring, enabling precise molecular modifications. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic moiety for enhanced metabolic stability and bioavailability.
  • Agrochemical Synthesis: Used in the development of modern pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence profiles.
  • Liquid Crystal & OLED Material Research: Acts as a starting material for creating fluorinated aromatic cores in electronic and photonic materials, influencing their dielectric and emissive properties.
  • Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and hydrolysis reactions to access 3-fluorobenzoic acid derivatives.
  • Fluorine Chemistry Research: A standard reagent for studying the effects of meta-fluorine substitution on reaction kinetics and electronic properties in aromatic systems.
  • Polymer Modification: Can be incorporated into polymer backbones or used to synthesize monomers for specialty polymers with specific chemical resistance or surface properties.

Basic Information

Item Detail
Product Name Methyl 3-Fluorobenzoate
CAS No. 455-68-5
Molecular Formula C8H7FO2
Molecular Weight 154.14 g/mol
Synonyms 3-Fluorobenzoic Acid Methyl Ester; Methyl m-Fluorobenzoate; m-Fluorobenzoic Acid Methyl Ester; Benzoic acid, 3-fluoro-, methyl ester; Methyl 3-fluorobenzenecarboxylate; 3-Fluoromethylbenzoate; Methyl ester of 3-fluorobenzoic acid
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Quality Control

Our Methyl 3-Fluorobenzoate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC/HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets precise customer specifications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with your R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item Specification
Appearance Colorless to pale yellow clear liquid
Identification (IR) Conforms to structure
Purity (GC/HPLC) ≥98.0% (Standard Grade)
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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