Description

2-Fluorocinnamic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where the introduction of a fluorine atom can dramatically alter biological activity and physicochemical properties. It is particularly valuable for researchers and manufacturers in the life sciences and specialty chemical sectors seeking to create novel compounds with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides with improved efficacy.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals.
• Biochemical Probe Development: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and probe molecule creation.
• Organic Synthesis: A versatile reagent for cross-coupling reactions, such as Heck reactions, and for introducing the cinnamic acid scaffold.

Basic Information

Product Name	2-Fluorocinnamic Acid
CAS No.	451-69-4
Molecular Formula	C9H7FO2
Molecular Weight	166.15 g/mol
Synonyms	(E)-3-(2-Fluorophenyl)acrylic Acid; 2-Fluorocinnamic Acid; trans-2-Fluorocinnamic Acid; (E)-2-Fluorocinnamic Acid; 3-(2-Fluorophenyl)-2-propenoic Acid; β-(2-Fluorophenyl)acrylic Acid; 2-Fluorobenzeneacrylic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluorocinnamic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.