Description

2-Methoxy-4-(Trifluoromethyl)Benzoic Acid is a high-value trifluoromethylated aromatic building block prized for its ability to impart metabolic stability and lipophilicity to target molecules. This compound is essential for research and development in advanced organic synthesis, particularly in the creation of novel active pharmaceutical ingredients (APIs) and agrochemicals. It serves as a critical intermediate for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials.
• Complex Ligand Synthesis: Useful for creating specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Methoxy-4-(Trifluoromethyl)Benzoic Acid
CAS No.	448-36-2
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	4-(Trifluoromethyl)-2-methoxybenzoic acid; 2-Methoxy-α,α,α-trifluoro-p-toluic acid; 2-Methoxy-4-trifluoromethylbenzoic acid; Benzoic acid, 2-methoxy-4-(trifluoromethyl)-; 4-Trifluoromethyl-2-methoxybenzoic acid; 2-Methoxy-4-(trifluoromethyl)benzoic acid; α,α,α-Trifluoro-2-methoxy-4-methylbenzoic acid
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature: 2-25°C. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.