Description

2-Amino-4-Fluorobenzoic Acid is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an amino and a carboxylic acid group on a fluorinated benzene ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drugs targeting central nervous system disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorinated properties.
• Dye and Pigment Intermediate: Acts as a building block for manufacturing specialized fluorinated dyes and pigments with unique color fastness and spectral properties.
• Bioconjugation and Probe Synthesis: Utilized in life sciences for creating fluorescent probes, biomarkers, and other molecular tools for diagnostic and research applications.

Basic Information

Product Name	2-Amino-4-Fluorobenzoic Acid
CAS No.	446-32-2
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	4-Fluoro-2-aminobenzoic Acid; 2-Amino-4-fluorobenzoic Acid; 4-Fluoroanthranilic Acid; Benzoic acid, 2-amino-4-fluoro-; 2-Carboxy-5-fluoroaniline; 5-Fluoroanthranilic Acid; 4-Fluoro-2-aminobenzoic acid; 2-Amino-4-fluorobenzoic acid
EINECS	207-175-2

Quality Control

Our 2-Amino-4-Fluorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For customers with specific regulatory needs, we can support documentation for GMP, ISO, or REACH compliance upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed after opening to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	195°C - 200°C
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.