Description

4-Chloro-2-Fluorobenzoic Acid is a versatile fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an essential intermediate for creating complex molecules with tailored properties. This compound is particularly valuable for research and development chemists and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated and chlorinated aromatic systems for enhanced bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine and chlorine substituents contribute to efficacy and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into polymer chains to alter physical properties such as thermal stability, chemical resistance, and dielectric constant.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Heck) and as a carboxylic acid feedstock for amide and ester formation in custom synthesis projects.
• Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and developing novel fluorinated compounds.

Basic Information

Product Name	4-Chloro-2-Fluorobenzoic Acid
CAS No.	446-30-0
Molecular Formula	C7H4ClFO2
Molecular Weight	174.56 g/mol
Synonyms	2-Fluoro-4-chlorobenzoic Acid; 4-Chloro-2-fluorobenzoic Acid; Benzoic acid, 4-chloro-2-fluoro-; 4-Chloro-2-fluorobenzenecarboxylic Acid; 2-Fluoro-4-chlorobenzenecarboxylic Acid; NSC 403121; 4-Chloro-2-fluoro-benzoic acid; 4-Chloro-2-fluorobenzoic acid (9CI)
EINECS	207-173-2

Quality Control

Our 4-Chloro-2-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical development and specialty chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	164°C - 168°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.