Description

2,4,5-Trifluorobenzoic Acid is a versatile fluorinated aromatic building block of significant commercial importance. Its trifluoromethyl-substituted benzoic acid structure makes it a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs). This high-purity compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries, where its unique electronic properties are leveraged to modify molecular characteristics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity, stability, and lipophilicity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Polymer & Resin Modifier: Incorporated into specialty polymers and epoxy resins to impart enhanced chemical resistance, thermal stability, and lower dielectric constants.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and as a precursor for corresponding acid chlorides, esters, and amides in complex molecule construction.
• Research & Development: Utilized in academic and industrial R&D for exploring new fluorinated compounds and materials science applications.

Basic Information

Item	Details
Product Name	2,4,5-Trifluorobenzoic Acid
CAS No.	446-17-3
Molecular Formula	C7H3F3O2
Molecular Weight	188.09 g/mol
Synonyms	2,4,5-Trifluorobenzenecarboxylic Acid; Benzoic acid, 2,4,5-trifluoro-; 2,4,5-Trifluorobenzoic acid; 446-17-3; NSC 221987; AI3-52202; 2,4,5-Trifluoro-benzoic acid; MFCD00004173
EINECS	207-174-2

Quality Control

Our 2,4,5-Trifluorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for pharmaceutical and advanced material synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	108-112 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.