Description

2-Amino-5-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of an amino group and a fluorine atom on the aromatic ring, enabling precise molecular modifications. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, including potential anticancer, antiviral, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, pesticides, and fungicides that benefit from the metabolic stability imparted by the fluorine atom.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and other functional materials.
• Fluorescent Dye and Probe Synthesis: Acts as a starting material for constructing fluorophore cores used in bio-imaging and diagnostics.
• Academic and R&D Laboratories: Used extensively in medicinal chemistry and organic synthesis research for structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-Amino-5-Fluorobenzoic Acid
CAS No.	446-08-2
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	5-Fluoroanthranilic Acid; 2-Amino-5-fluorobenzoic acid; 5-Fluoro-2-aminobenzoic Acid; Benzoic acid, 2-amino-5-fluoro-; 5-Fluoranthranilsäure (German); Acide 5-fluoro-2-aminobenzoïque (French); 446-08-2; 5-Fluoroanthranilic acid
EINECS	207-174-5

Quality Control

Our 2-Amino-5-Fluorobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	168°C - 172°C
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.