Description

2-Fluorobenzamide is a versatile fluorinated aromatic amide serving as a critical building block in advanced organic synthesis. Its value lies in the strategic introduction of a fluorine atom, which can dramatically alter the physicochemical and biological properties of target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, enabling the development of novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides where the fluorine atom enhances bioavailability and environmental stability.
• Liquid Crystal & OLED Material Development: Serves as a building block for fluorinated organic electronic materials, improving charge transport and thermal stability.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, amide bond transformations, and as a directing group in metal-catalyzed C-H functionalization.
• Fluorine Chemistry Research: Fundamental compound for studying structure-activity relationships (SAR) and the effects of fluorination in medicinal and material chemistry.

Basic Information

Product Name	2-Fluorobenzamide
CAS No.	445-28-3
Molecular Formula	C7H6FNO
Molecular Weight	139.13 g/mol
Synonyms	o-Fluorobenzamide; 2-Fluorobenzoic acid amide; Benzoamide, 2-fluoro-; Ortho-fluorobenzamide; 2-Fluorobenzenecarboxamide; NSC 403697; AI3-52296; CCRIS 9355
EINECS	207-166-5

Quality Control

Our 2-Fluorobenzamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and FT-IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	142 - 146 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.