Description

(3-Fluoro-Phenoxy)-Acetic Acid is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a phenoxyacetic acid scaffold with a fluorine substituent, enabling precise modulation of electronic properties, lipophilicity, and metabolic stability in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients, including potential herbicides, pharmaceuticals, and liquid crystal materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new drug candidates, particularly where fluorine incorporation is desired to enhance bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and plant growth regulators, leveraging the phenoxyacetic acid moiety's biological activity.
• Liquid Crystal Materials: Serves as a fluorinated component in the synthesis of specialty chemicals for electronic displays, where fluorine atoms improve stability and electro-optical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and amide formations to introduce the (3-fluorophenoxy)acetyl group into more complex molecular architectures.
• Biochemical Research: Utilized as a probe or substrate in enzymatic studies and for the synthesis of labeled compounds for metabolic pathway tracing.

Basic Information

Product Name	(3-Fluoro-Phenoxy)-Acetic Acid
CAS No.	404-98-8
Molecular Formula	C8H7FO3
Molecular Weight	170.14 g/mol
Synonyms	2-(3-Fluorophenoxy)acetic Acid; 3-Fluorophenoxyacetic Acid; (3-Fluorophenoxy)ethanoic Acid; NSC 403714; 3-FPA; α-Carboxymethyl-3-fluorophenyl Ether; 3-Fluorophenoxy Acetic Acid
EINECS	Contact for details

Quality Control

Our (3-Fluoro-Phenoxy)-Acetic Acid is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, and is supplied with a detailed Certificate of Analysis (COA) to meet the stringent requirements of research and cGMP-grade production environments. We adhere to relevant industry standards and can provide material tailored to specific customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its acidic nature, ensure containers are made of compatible materials and are properly sealed to maintain integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.