Description

Benzoic Acid, 5-(Fluorosulfonyl)-2-Hydroxy- is a specialized aromatic compound featuring both a sulfonyl fluoride and a phenolic hydroxyl group, making it a valuable multifunctional building block. This unique structure provides exceptional reactivity for synthesizing complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs and other bioactive molecules targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the sulfonyl fluoride moiety for potent biological activity.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, coatings, and advanced functional materials.
• Chemical Biology & Proteomics: Acts as a reactive handle in activity-based protein profiling (ABPP) and the development of covalent enzyme inhibitors due to the sulfonyl fluoride group's selectivity.
• Ligand & Catalyst Development: Utilized for constructing complex chelating ligands and organocatalysts in asymmetric synthesis.
• Fluorescent Probe Synthesis: Building block for creating sensitive molecular probes and sensors used in diagnostic assays and cellular imaging.

Basic Information

Product Name	Benzoic Acid, 5-(Fluorosulfonyl)-2-Hydroxy-
CAS No.	400-96-4
Molecular Formula	C7H5FO5S
Molecular Weight	220.17 g/mol
Synonyms	2-Hydroxy-5-(fluorosulfonyl)benzoic acid; 5-Fluorosulfonylsalicylic acid; 2-Hydroxy-5-fluorosulfonylbenzoic acid; Salicylic acid, 5-(fluorosulfonyl)-; 5-(Fluorosulfonyl)salicylic acid; Benzoic acid, 2-hydroxy-5-(fluorosulfonyl)-
EINECS	Contact for details

Quality Control

Every batch of Benzoic Acid, 5-(Fluorosulfonyl)-2-Hydroxy- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each shipment to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.