Description

3-Fluoro-4-Methyl-5-Nitro-Benzoic Acid is a versatile aromatic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring fluorine, methyl, and nitro substituents, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a fluorinated aromatic core.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and stability.
• Material Science: Building block for advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro and carboxylic acid groups.
• Dye and Pigment Synthesis: Intermediate for manufacturing specialized azo dyes and pigments where the substituents influence color and fastness properties.
• Chemical Research & Development: A valuable reagent for academic and industrial research in medicinal chemistry and organic methodology development.
• Coordination Chemistry: Can act as a ligand or precursor for metal-organic frameworks (MOFs) and catalysts.

Basic Information

Product Name	3-Fluoro-4-Methyl-5-Nitro-Benzoic Acid
CAS No.	400-88-4
Molecular Formula	C8H6FNO4
Molecular Weight	199.14 g/mol
Synonyms	5-Nitro-3-fluoro-4-methylbenzoic acid; 3-Fluoro-4-methyl-5-nitrobenzoic acid; Benzoic acid, 3-fluoro-4-methyl-5-nitro-; 400-88-4; 4-Methyl-3-fluoro-5-nitrobenzoic acid; 3-Fluoro-4-methyl-5-nitro-benzoic acid; 3-Fluoro-4-methyl-5-nitrobenzoic acid (CAS 400-88-4)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methyl-5-Nitro-Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.